{"id":6452,"date":"2025-07-27T23:51:20","date_gmt":"2025-07-27T20:51:20","guid":{"rendered":"https:\/\/www.rheumatology.bg\/?p=6452"},"modified":"2025-07-27T23:51:20","modified_gmt":"2025-07-27T20:51:20","slug":"%d0%bd%d0%be%d0%b2-%d0%b4%d0%b2%d0%be%d0%b5%d0%bd-jak-rock-%d0%b8%d0%bd%d1%85%d0%b8%d0%b1%d0%b8%d1%82%d0%be%d1%80-%d0%bf%d0%be%d0%ba%d0%b0%d0%b7%d0%b2%d0%b0-%d0%be%d0%b1%d0%b5%d1%89%d0%b0%d0%b2%d0%b0","status":"publish","type":"post","link":"https:\/\/www.rheumatology.bg\/?p=6452","title":{"rendered":"\u041d\u043e\u0432 \u0434\u0432\u043e\u0435\u043d JAK-ROCK \u0438\u043d\u0445\u0438\u0431\u0438\u0442\u043e\u0440 \u043f\u043e\u043a\u0430\u0437\u0432\u0430 \u043e\u0431\u0435\u0449\u0430\u0432\u0430\u0449\u0438 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438 \u043f\u0440\u0438 \u0430\u043a\u0442\u0438\u0432\u0435\u043d \u0440\u0435\u0432\u043c\u0430\u0442\u043e\u0438\u0434\u0435\u043d \u0430\u0440\u0442\u0440\u0438\u0442"},"content":{"rendered":"<p>\u041d\u043e\u0432 \u0435\u043a\u0441\u043f\u0435\u0440\u0438\u043c\u0435\u043d\u0442\u0430\u043b\u0435\u043d <strong data-start=\"320\" data-end=\"400\">\u0434\u0432\u043e\u0435\u043d \u0438\u043d\u0445\u0438\u0431\u0438\u0442\u043e\u0440 \u043d\u0430 JAK (Janus kinase) \u0438 ROCK (Rho-associated protein kinase)<\/strong> \u2014 <strong data-start=\"403\" data-end=\"414\">CPL\u2019116 <\/strong>\u0435 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u0435\u043d \u043f\u0440\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0441 \u0440\u0435\u0432\u043c\u0430\u0442\u043e\u0438\u0434\u0435\u043d \u0430\u0440\u0442\u0440\u0438\u0442. \u041f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0430\u0442\u044a \u0441\u0435 \u043f\u043e\u043d\u0430\u0441\u044f \u0434\u043e\u0431\u0440\u0435,\u00a0\u0431\u0435\u0437 \u0442\u0438\u043f\u0438\u0447\u043d\u0438\u0442\u0435 \u0441\u0442\u0440\u0430\u043d\u0438\u0447\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438, \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u043d\u0438 \u0437\u0430 JAK \u0438\u043d\u0445\u0438\u0431\u0438\u0442\u043e\u0440\u0438\u0442\u0435.<\/p>\n<p>\u0412 \u043c\u043d\u043e\u0433\u043e\u0446\u0435\u043d\u0442\u0440\u043e\u0432\u043e \u043a\u043b\u0438\u043d\u0438\u0447\u043d\u043e <strong>\u043f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435 \u0444\u0430\u0437\u0430 2<\/strong>, \u043f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u043e \u0432 \u0434\u0435\u0432\u0435\u0442 \u0431\u043e\u043b\u043d\u0438\u0446\u0438 \u0438 \u043a\u043b\u0438\u043d\u0438\u043a\u0438 \u0432 \u041f\u043e\u043b\u0448\u0430 \u0438 \u0423\u043a\u0440\u0430\u0439\u043d\u0430, \u0431\u0438\u043b\u0430 \u043e\u0446\u0435\u043d\u0435\u043d\u0430 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0442\u0430 \u0438 \u0431\u0435\u0437\u043e\u043f\u0430\u0441\u043d\u043e\u0441\u0442\u0442\u0430 \u043d\u0430 CPL\u2019116 \u043f\u0440\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0441 \u0430\u043a\u0442\u0438\u0432\u0435\u043d \u0440\u0435\u0432\u043c\u0430\u0442\u043e\u0438\u0434\u0435\u043d \u0430\u0440\u0442\u0440\u0438\u0442, \u0441 \u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u044a\u0447\u0435\u043d \u043e\u0442\u0433\u043e\u0432\u043e\u0440 \u043d\u0430 \u043c\u0435\u0442\u043e\u0442\u0440\u0435\u043a\u0441\u0430\u0442.<\/p>\n<ul data-start=\"768\" data-end=\"1080\">\n<li data-start=\"768\" data-end=\"846\">\n<p data-start=\"770\" data-end=\"846\">\u0423\u0447\u0430\u0441\u0442\u0432\u0430\u043b\u0438 <strong data-start=\"780\" data-end=\"806\">106 \u0432\u044a\u0437\u0440\u0430\u0441\u0442\u043d\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438<\/strong> (\u0441\u0440\u0435\u0434\u043d\u0430 \u0432\u044a\u0437\u0440\u0430\u0441\u0442: 54.4 \u0433\u043e\u0434\u0438\u043d\u0438, 75% \u0436\u0435\u043d\u0438)<\/p>\n<\/li>\n<li data-start=\"847\" data-end=\"1080\">\n<p data-start=\"849\" data-end=\"978\">\u041f\u0430\u0446\u0438\u0435\u043d\u0442\u0438\u0442\u0435 \u0431\u0438\u043b\u0438 <strong data-start=\"865\" data-end=\"882\">\u0440\u0430\u043d\u0434\u043e\u043c\u0438\u0437\u0438\u0440\u0430\u043d\u0438<\/strong> \u0434\u0430 \u043f\u043e\u043b\u0443\u0447\u0430\u0432\u0430\u0442 <strong data-start=\"896\" data-end=\"961\">\u043f\u0435\u0440\u043e\u0440\u0430\u043b\u0435\u043d CPL\u2019116 \u0434\u0432\u0430 \u043f\u044a\u0442\u0438 \u0434\u043d\u0435\u0432\u043d\u043e \u0432 \u043f\u0440\u043e\u0434\u044a\u043b\u0436\u0435\u043d\u0438\u0435 \u043d\u0430 12 \u0441\u0435\u0434\u043c\u0438\u0446\u0438<\/strong> \u0432 \u0441\u043b\u0435\u0434\u043d\u0438\u0442\u0435 \u0434\u043e\u0437\u0438:<\/p>\n<ul data-start=\"981\" data-end=\"1080\">\n<li data-start=\"981\" data-end=\"1003\">\n<p data-start=\"983\" data-end=\"1003\"><strong data-start=\"983\" data-end=\"992\">60 mg<\/strong> (n = 27)<\/p>\n<\/li>\n<li data-start=\"1006\" data-end=\"1029\">\n<p data-start=\"1008\" data-end=\"1029\"><strong data-start=\"1008\" data-end=\"1018\">120 mg<\/strong> (n = 25)<\/p>\n<\/li>\n<li data-start=\"1032\" data-end=\"1055\">\n<p data-start=\"1034\" data-end=\"1055\"><strong data-start=\"1034\" data-end=\"1044\">240 mg<\/strong> (n = 26)<\/p>\n<\/li>\n<li data-start=\"1058\" data-end=\"1080\">\n<p data-start=\"1060\" data-end=\"1080\"><strong data-start=\"1060\" data-end=\"1071\">\u043f\u043b\u0430\u0446\u0435\u0431\u043e<\/strong> (n = 28)<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p data-start=\"1082\" data-end=\"1212\">\u041e\u0441\u043d\u043e\u0432\u043d\u0430\u0442\u0430 \u043a\u0440\u0430\u0439\u043d\u0430 \u0442\u043e\u0447\u043a\u0430 \u0431\u0438\u043b\u0430 <strong data-start=\"1110\" data-end=\"1194\">\u043f\u0440\u043e\u043c\u044f\u043d\u0430\u0442\u0430 \u0432 Disease Activity Score \u043d\u0430 28 \u0441\u0442\u0430\u0432\u0438 \u0441 C-\u0440\u0435\u0430\u043a\u0442\u0438\u0432\u0435\u043d \u043f\u0440\u043e\u0442\u0435\u0438\u043d (DAS28-CRP)<\/strong> \u043d\u0430 12-\u0442\u0430 \u0441\u0435\u0434\u043c\u0438\u0446\u0430.<\/p>\n<h3 data-start=\"1219\" data-end=\"1232\">\u0420\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438<\/h3>\n<ul data-start=\"1234\" data-end=\"1666\">\n<li data-start=\"1234\" data-end=\"1371\">\n<p data-start=\"1236\" data-end=\"1306\">\u0421\u0430\u043c\u043e <strong data-start=\"1241\" data-end=\"1261\">\u0434\u043e\u0437\u0430\u0442\u0430 \u043e\u0442 240 mg<\/strong> \u0434\u043e\u0432\u0435\u043b\u0430 \u0434\u043e <strong data-start=\"1272\" data-end=\"1305\">\u0437\u043d\u0430\u0447\u0438\u043c\u043e \u043d\u0430\u043c\u0430\u043b\u0435\u043d\u0438\u0435 \u0432 DAS28-CRP<\/strong>:<\/p>\n<ul data-start=\"1309\" data-end=\"1371\">\n<li data-start=\"1309\" data-end=\"1371\">\n<p data-start=\"1311\" data-end=\"1371\"><em data-start=\"1311\" data-end=\"1371\">\u0441\u0440\u0435\u0434\u043d\u0430 \u043a\u043e\u0440\u0438\u0433\u0438\u0440\u0430\u043d\u0430 \u0440\u0430\u0437\u043b\u0438\u043a\u0430 \u0441\u043f\u0440\u044f\u043c\u043e \u043f\u043b\u0430\u0446\u0435\u0431\u043e: -0.89; P = 0.010<\/em><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<li data-start=\"1372\" data-end=\"1488\">\n<p data-start=\"1374\" data-end=\"1488\">\u041f\u043e-\u043d\u0438\u0441\u043a\u0438\u0442\u0435 \u0434\u043e\u0437\u0438 (60 mg \u0438 120 mg) <strong data-start=\"1407\" data-end=\"1448\">\u043d\u0435 \u0434\u043e\u0441\u0442\u0438\u0433\u043d\u0430\u043b\u0438 \u0441\u0442\u0430\u0442\u0438\u0441\u0442\u0438\u0447\u0435\u0441\u043a\u0430 \u0437\u043d\u0430\u0447\u0438\u043c\u043e\u0441\u0442<\/strong> \u043f\u043e \u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u0435 \u043d\u0430 \u043e\u0441\u043d\u043e\u0432\u043d\u0430\u0442\u0430 \u043a\u0440\u0430\u0439\u043d\u0430 \u0442\u043e\u0447\u043a\u0430.<\/p>\n<\/li>\n<li data-start=\"1489\" data-end=\"1666\">\n<p data-start=\"1491\" data-end=\"1666\">\u041d\u0435 \u0431\u0438\u043b\u0438 \u043e\u0442\u0447\u0435\u0442\u0435\u043d\u0438 <strong data-start=\"1508\" data-end=\"1545\">\u0437\u043d\u0430\u0447\u0438\u043c\u0438 \u043f\u0440\u043e\u043c\u0435\u043d\u0438 \u0432 \u043b\u0438\u043f\u0438\u0434\u043d\u0438\u044f \u043f\u0440\u043e\u0444\u0438\u043b<\/strong> (\u043e\u0431\u0449, LDL, HDL \u0445\u043e\u043b\u0435\u0441\u0442\u0435\u0440\u043e\u043b, \u0442\u0440\u0438\u0433\u043b\u0438\u0446\u0435\u0440\u0438\u0434\u0438) \u0438\u043b\u0438 <strong data-start=\"1591\" data-end=\"1608\">\u043a\u0440\u0435\u0430\u0442\u0438\u043d\u043a\u0438\u043d\u0430\u0437\u0430<\/strong> \u043f\u0440\u0438 \u043d\u0438\u043a\u043e\u044f \u043e\u0442 \u0433\u0440\u0443\u043f\u0438\u0442\u0435, \u043b\u0435\u043a\u0443\u0432\u0430\u043d\u0438 \u0441 CPL\u2019116, \u0441\u043f\u0440\u044f\u043c\u043e \u043f\u043b\u0430\u0446\u0435\u0431\u043e.<\/p>\n<\/li>\n<\/ul>\n<h3 data-start=\"1673\" data-end=\"1693\">\u041d\u0435\u0436\u0435\u043b\u0430\u043d\u0438 \u0441\u044a\u0431\u0438\u0442\u0438\u044f<\/h3>\n<ul data-start=\"1695\" data-end=\"1965\">\n<li data-start=\"1695\" data-end=\"1849\">\n<p data-start=\"1697\" data-end=\"1849\">\u041d\u0430 <strong data-start=\"1700\" data-end=\"1716\">2-\u0442\u0430 \u0441\u0435\u0434\u043c\u0438\u0446\u0430<\/strong> \u0432 \u0433\u0440\u0443\u043f\u0430\u0442\u0430 \u0441 60 mg \u0441\u0435 \u043f\u043e\u044f\u0432\u0438\u043b <strong data-start=\"1745\" data-end=\"1804\">\u0441\u043b\u0443\u0447\u0430\u0439 \u043d\u0430 \u043d\u0435\u0444\u0430\u0442\u0430\u043b\u0435\u043d \u0438\u043d\u0444\u0430\u0440\u043a\u0442 \u043d\u0430 \u043c\u0438\u043e\u043a\u0430\u0440\u0434\u0430 \u0431\u0435\u0437 ST-\u0435\u043b\u0435\u0432\u0430\u0446\u0438\u044f<\/strong>, \u043a\u043e\u0439\u0442\u043e <strong data-start=\"1812\" data-end=\"1834\">\u043c\u043e\u0436\u0435 \u0434\u0430 \u0435 \u0441\u0432\u044a\u0440\u0437\u0430\u043d<\/strong> \u0441 \u043b\u0435\u043a\u0430\u0440\u0441\u0442\u0432\u043e\u0442\u043e.<\/p>\n<\/li>\n<li data-start=\"1850\" data-end=\"1965\">\n<p data-start=\"1852\" data-end=\"1965\">\u0412 \u0433\u0440\u0443\u043f\u0430\u0442\u0430 \u0441 240 mg \u0431\u0438\u043b \u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u0446\u0438\u0440\u0430\u043d <strong data-start=\"1890\" data-end=\"1915\">\u0440\u0430\u043a \u043d\u0430 \u043f\u0438\u043a\u043e\u0447\u043d\u0438\u044f \u043c\u0435\u0445\u0443\u0440<\/strong>, \u043d\u043e \u0442\u043e\u0439 <strong data-start=\"1924\" data-end=\"1952\">\u043d\u0435 \u0431\u0438\u043b \u0441\u0447\u0435\u0442\u0435\u043d \u0437\u0430 \u0441\u0432\u044a\u0440\u0437\u0430\u043d<\/strong> \u0441 \u0442\u0435\u0440\u0430\u043f\u0438\u044f\u0442\u0430.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"1972\" data-end=\"1996\"><span style=\"font-size: 16px;\">\u041d\u043e\u0432\u0438\u044f\u0442 \u043c\u0435\u0445\u0430\u043d\u0438\u0437\u044a\u043c \u043d\u0430 \u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435 \u0435 \u0438\u043d\u0442\u0440\u0438\u0433\u0443\u0432\u0430\u0449, \u0430 \u0438\u0434\u0435\u044f\u0442\u0430, \u0447\u0435 \u0435\u0434\u043d\u043e\u0432\u0440\u0435\u043c\u0435\u043d\u043d\u043e\u0442\u043e \u0442\u0430\u0440\u0433\u0435\u0442\u0438\u0440\u0430\u043d\u0435 \u043d\u0430 ROCK \u0438 JAK \u043c\u043e\u0436\u0435 \u0434\u0430 \u043d\u0435\u0443\u0442\u0440\u0430\u043b\u0438\u0437\u0438\u0440\u0430 \u043d\u0435\u0433\u0430\u0442\u0438\u0432\u043d\u0438\u0442\u0435 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0442\u043d\u0438 \u0435\u0444\u0435\u043a\u0442\u0438 \u043d\u0430 JAK-\u0438\u043d\u0445\u0438\u0431\u0438\u0442\u043e\u0440\u0438\u0442\u0435, \u0435 \u043e\u0441\u043e\u0431\u0435\u043d\u043e \u0438\u043d\u0442\u0435\u0440\u0435\u0441\u043d\u0430, \u043a\u043e\u043c\u0435\u043d\u0442\u0438\u0440\u0430\u0442 \u0430\u0432\u0442\u043e\u0440\u0438\u0442\u0435 \u0432 \u043f\u0440\u0438\u0434\u0440\u0443\u0436\u0430\u0432\u0430\u0449\u0430\u0442\u0430 \u0440\u0435\u0434\u0430\u043a\u0446\u0438\u043e\u043d\u043d\u0430 \u0441\u0442\u0430\u0442\u0438\u044f.<\/span><\/p>\n<p data-start=\"2000\" data-end=\"2362\">\u041f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435\u0442\u043e \u0438\u043c\u0430 \u0438 \u0441\u0432\u043e\u0438\u0442\u0435 \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u0438\u044f:<\/p>\n<ul data-start=\"2401\" data-end=\"2878\">\n<li data-start=\"2401\" data-end=\"2592\">\n<p data-start=\"2403\" data-end=\"2592\">\u041f\u0440\u043e\u0443\u0447\u0432\u0430\u043d\u0435\u0442\u043e \u0431\u0438\u043b\u043e \u043f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u043e <strong data-start=\"2430\" data-end=\"2458\">\u0438\u0437\u0446\u044f\u043b\u043e \u0432 \u041f\u043e\u043b\u0448\u0430 \u0438 \u0423\u043a\u0440\u0430\u0439\u043d\u0430<\/strong>, \u043a\u0430\u0442\u043e <strong data-start=\"2465\" data-end=\"2515\">\u0432\u0441\u0438\u0447\u043a\u0438 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u0446\u0438 \u0431\u0438\u043b\u0438 \u0441 \u0431\u044f\u043b \u0435\u0442\u043d\u0438\u0447\u0435\u0441\u043a\u0438 \u043f\u0440\u043e\u0438\u0437\u0445\u043e\u0434<\/strong>, \u043a\u043e\u0435\u0442\u043e <strong data-start=\"2523\" data-end=\"2557\">\u043c\u043e\u0436\u0435 \u0434\u0430 \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0438 \u043f\u0440\u0438\u043b\u043e\u0436\u0438\u043c\u043e\u0441\u0442\u0442\u0430<\/strong> \u043d\u0430 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438\u0442\u0435 \u0437\u0430 \u0434\u0440\u0443\u0433\u0438 \u043f\u043e\u043f\u0443\u043b\u0430\u0446\u0438\u0438.<\/p>\n<\/li>\n<li data-start=\"2593\" data-end=\"2726\">\n<p data-start=\"2595\" data-end=\"2726\">\u0412\u043e\u0435\u043d\u043d\u0438\u044f\u0442 \u043a\u043e\u043d\u0444\u043b\u0438\u043a\u0442 \u0432 \u0423\u043a\u0440\u0430\u0439\u043d\u0430 <strong data-start=\"2623\" data-end=\"2687\">\u0432\u044a\u0437\u043c\u043e\u0436\u043d\u043e \u0435 \u0437\u0430\u0442\u0440\u0443\u0434\u043d\u0438\u043b \u0434\u043e\u0441\u0442\u044a\u043f\u0430 \u0434\u043e \u043d\u0430\u043f\u0440\u0435\u0434\u043d\u0430\u043b\u0438 \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438 \u0443\u0441\u043b\u0443\u0433\u0438<\/strong>, \u043a\u043e\u0435\u0442\u043e \u0441\u044a\u0449\u043e \u0435 \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b\u043d\u043e \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u0438\u0435.<\/p>\n<\/li>\n<li data-start=\"2727\" data-end=\"2878\">\n<p data-start=\"2729\" data-end=\"2878\">\u0412\u0441\u0438\u0447\u043a\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0431\u0438\u043b\u0438 \u0441 <strong data-start=\"2752\" data-end=\"2791\">\u043d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u044a\u0447\u0435\u043d \u043e\u0442\u0433\u043e\u0432\u043e\u0440 \u043d\u0430 \u043c\u0435\u0442\u043e\u0442\u0440\u0435\u043a\u0441\u0430\u0442<\/strong>, \u043a\u043e\u0435\u0442\u043e <strong data-start=\"2799\" data-end=\"2838\">\u0441\u0442\u0435\u0441\u043d\u044f\u0432\u0430 \u0432\u044a\u0437\u043c\u043e\u0436\u043d\u043e\u0441\u0442\u0442\u0430 \u0437\u0430 \u043e\u0431\u043e\u0431\u0449\u0430\u0432\u0430\u043d\u0435<\/strong> \u043d\u0430 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438\u0442\u0435 \u0437\u0430 \u0432\u0441\u0438\u0447\u043a\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0441 \u0420\u0410.<\/p>\n<\/li>\n<\/ul>\n<p><a href=\"https:\/\/www.medscape.com\/viewarticle\/dual-jak-rock-inhibitor-shows-promise-active-ra-2025a1000h9y\"><strong>\u0418\u0437\u0442\u043e\u0447\u043d\u0438\u043a<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<div class=\"mh-excerpt\"><p>\u041d\u043e\u0432 \u0435\u043a\u0441\u043f\u0435\u0440\u0438\u043c\u0435\u043d\u0442\u0430\u043b\u0435\u043d \u0434\u0432\u043e\u0435\u043d \u0438\u043d\u0445\u0438\u0431\u0438\u0442\u043e\u0440 \u043d\u0430 JAK (Janus kinase) \u0438 ROCK (Rho-associated protein kinase) \u2014 CPL\u2019116 \u0435 \u0435\u0444\u0435\u043a\u0442\u0438\u0432\u0435\u043d \u043f\u0440\u0438 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0438 \u0441 <a class=\"mh-excerpt-more\" href=\"https:\/\/www.rheumatology.bg\/?p=6452\" title=\"\u041d\u043e\u0432 \u0434\u0432\u043e\u0435\u043d JAK-ROCK \u0438\u043d\u0445\u0438\u0431\u0438\u0442\u043e\u0440 \u043f\u043e\u043a\u0430\u0437\u0432\u0430 \u043e\u0431\u0435\u0449\u0430\u0432\u0430\u0449\u0438 \u0440\u0435\u0437\u0443\u043b\u0442\u0430\u0442\u0438 \u043f\u0440\u0438 \u0430\u043a\u0442\u0438\u0432\u0435\u043d \u0440\u0435\u0432\u043c\u0430\u0442\u043e\u0438\u0434\u0435\u043d \u0430\u0440\u0442\u0440\u0438\u0442\">[&#8230;]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":6454,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[44],"tags":[],"class_list":["post-6452","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog"],"_links":{"self":[{"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=\/wp\/v2\/posts\/6452","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6452"}],"version-history":[{"count":2,"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=\/wp\/v2\/posts\/6452\/revisions"}],"predecessor-version":[{"id":6455,"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=\/wp\/v2\/posts\/6452\/revisions\/6455"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=\/wp\/v2\/media\/6454"}],"wp:attachment":[{"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6452"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6452"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.rheumatology.bg\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6452"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}